TET2-AS1

Across TCGA patient cohorts, TET2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,853 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TET2-AS1-associated GO terms across cancer lineages are Organelle disassembly, Establishment or maintenance of cell polarity, and Negative regulation of cellular catabolic process. Each is linked with TET2-AS1 in more than 23 cancer types. Because this analysis shows association rather than direction, both TET2-AS1-to-partner and partner-to-TET2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle disassembly grouped by TET2-AS1-low versus TET2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TET2-AS1→partner) and Y-score (partner→TET2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Organelle disassembly →	+0.055	+0.348	<.001	<.001	3	24
ESCA	Establishment or maintenance of cell polarity →	+0.042	+0.306	<.001	<.001	3	24
ESCA	Negative regulation of cellular catabolic process →	+0.050	+0.421	<.001	<.001	3	23
ESCA	TOR signaling →	+0.046	+0.326	<.001	<.001	3	23
ESCA	Protein-containing complex disassembly →	+0.042	+0.323	<.001	<.001	3	23
ESCA	Cellular response to oxidative stress →	+0.043	+0.335	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,853 associations by consensus.

Organelle disassembly by TET2-AS1 expression — ESCA

Explore this box plot interactively →