TESMIN

Across TCGA patient cohorts, TESMIN protein abundance is significantly associated with the RNA expression of many other genes, with 1,159 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TESMIN-associated genes across cancer lineages are WNT3, TEX14, and RAMP2. Each is linked with TESMIN in more than 1 cancer types. Because this analysis shows association rather than direction, both TESMIN-to-partner and partner-to-TESMIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TESMIN versus WNT3 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TESMIN→partner) and Y-score (partner→TESMIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WNT3 →	+1.034	+0.603	<.001	<.001	3	2
BRCA	TEX14 →	+0.608	+0.421	.009	.006	3	2
OV	RAMP2 →	+1.529	+0.648	<.001	.003	3	2
OV	ZKSCAN2 →	+0.478	+0.509	.005	.005	3	2
BRCA	NXPH3 →	+1.384	+0.556	<.001	<.001	3	2
OV	TPTEP1 →	+1.057	+0.578	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,159 associations by consensus.

TESMIN vs WNT3 — BRCA

Explore this scatter interactively →