TES

Across TCGA patient cohorts, TES protein abundance is significantly associated with the RNA expression of many other genes, with 16,182 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TES-associated genes across cancer lineages are MET, CAV1, and FAM3C. Each is linked with TES in more than 7 cancer types. Because this analysis shows association rather than direction, both TES-to-partner and partner-to-TES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TES versus MET in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TES→partner) and Y-score (partner→TES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MET →	+2.434	+0.649	<.001	<.001	3	8
HNSC	CAV1 →	+1.275	+0.367	<.001	<.001	3	7
OV	FAM3C →	+0.806	+0.456	<.001	<.001	3	6
GBM	CCDC71L →	+0.867	+0.433	<.001	<.001	3	6
OV	CDK14 →	+1.175	+0.362	.001	.003	3	6
GBM	CAV2 →	+1.078	+0.498	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,182 associations by consensus.

TES vs MET — GBM

Explore this scatter interactively →