TES

Across TCGA cell cohorts, TES RNA expression is significantly associated with the go_rna of many other GO terms, with 3,088 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TES-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Membrane fission, and Regulation of intracellular transport. Each is linked with TES in more than 11 cancer types. Because this analysis shows association rather than direction, both TES-to-partner and partner-to-TES results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by TES-low versus TES-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TES→partner) and Y-score (partner→TES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Establishment of protein localization to membrane →	+0.043	+1.103	<.001	<.001	3	12
LIVER	Membrane fission →	+0.080	+1.813	<.001	.002	3	10
BREAST	Regulation of intracellular transport →	+0.055	+1.895	.001	.004	3	9
STOMACH	Positive regulation of phosphorylation →	+0.037	+2.172	.007	.008	3	9
LARGE_INTESTINE	Vesicle-mediated transport to the plasma membrane →	+0.048	+0.841	<.001	.001	3	8
PANCREAS	Cellular response to starvation →	+0.043	+1.203	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,088 associations by consensus.

Establishment of protein localization to membrane by TES expression — LARGE_INTESTINE

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