TERF2IP

Across TCGA cell cohorts, TERF2IP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,900 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TERF2IP-associated GO terms across cancer lineages are Regulation of intracellular steroid hormone receptor signaling pathway, Nuclear-transcribed mRNA catabolic process, and Golgi vesicle transport. Each is linked with TERF2IP in more than 9 cancer types. Because this analysis shows association rather than direction, both TERF2IP-to-partner and partner-to-TERF2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular steroid hormone receptor signaling pathway grouped by TERF2IP-low versus TERF2IP-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TERF2IP→partner) and Y-score (partner→TERF2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.067	+0.757	.001	.003	3	10
KIDNEY	Nuclear-transcribed mRNA catabolic process →	+0.057	+0.896	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.067	+0.747	<.001	<.001	3	10
LUNG_SCLC	Late viral transcription →	+0.110	+0.935	.001	.001	3	10
LUNG_SCLC	Transcription elongation-coupled chromatin remodeling →	+0.109	+1.052	<.001	<.001	3	10
BLOOD_Myeloma	Viral transcription →	+0.099	+0.936	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,900 associations by consensus.

Regulation of intracellular steroid hormone receptor signaling pathway by TERF2IP expression — BLOOD_Lymphoma

Explore this box plot interactively →