TERF2IP

Across TCGA cell cohorts, TERF2IP mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TERF2IP-associated genes across cancer lineages are MAGEB4, OR5C1, and IL20. Each is linked with TERF2IP in more than 1 cancer types. Because this analysis shows association rather than direction, both TERF2IP-to-partner and partner-to-TERF2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by TERF2IP-low versus TERF2IP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERF2IP→partner) and Y-score (partner→TERF2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1
LARGE_INTESTINE	OR5C1 →	+0.050	+3.793	<.001	.007	3	1
LARGE_INTESTINE	IL20 →	+0.262	+3.662	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MAGEB4 by TERF2IP expression — LARGE_INTESTINE

Explore this box plot interactively →