TERC

Across TCGA patient cohorts, TERC RNA expression is significantly associated with the go_rna of many other GO terms, with 6,657 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TERC-associated GO terms across cancer lineages are Regulation of organelle assembly, Regulation of canonical Wnt signaling pathway, and Protein-containing complex disassembly. Each is linked with TERC in more than 18 cancer types. Because this analysis shows association rather than direction, both TERC-to-partner and partner-to-TERC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by TERC-low versus TERC-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TERC→partner) and Y-score (partner→TERC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Regulation of organelle assembly →	+0.041	+0.527	<.001	<.001	3	19
UCS	Regulation of canonical Wnt signaling pathway →	+0.036	+0.488	<.001	<.001	3	18
LUSC	Protein-containing complex disassembly →	+0.018	+0.215	<.001	<.001	3	17
UCS	Regulation of chromatin organization →	+0.056	+0.482	<.001	<.001	3	17
UCS	Regulation of DNA repair →	+0.030	+0.419	<.001	.001	2	18
UCS	Regulation of double-strand break repair →	+0.040	+0.443	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,657 associations by consensus.

Regulation of organelle assembly by TERC expression — UCS

Explore this box plot interactively →