TERB1

Across TCGA cell cohorts, TERB1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TERB1-associated genes across cancer lineages are MAGEB5, OR1L1, and C6orf118. Each is linked with TERB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TERB1-to-partner and partner-to-TERB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by TERB1-low versus TERB1-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERB1→partner) and Y-score (partner→TERB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_SCLC	OR1L1 →	+0.031	+5.029	.001	.006	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+2.793	<.001	.002	3	1
LARGE_INTESTINE	OR4F4 →	+0.016	+3.009	<.001	.001	3	1
LARGE_INTESTINE	OR10R2 →	+0.017	+2.977	<.001	.006	3	1
LARGE_INTESTINE	FGF21 →	+0.302	+3.392	.007	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MAGEB5 by TERB1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →