TERB1

Across TCGA pan-cancer cohorts, TERB1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TERB1 data layer compared with 2 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher TERB1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TERB1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and BRCA show a favorable association.

DLBC, UVM, and KIRP are the cancer types where TERB1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Median	All	0.521	0.907	<.001	63	view →
UVM	DFS	Tertile	III,IV	0.382	0.794	.007	44	view →
KIRP	DFS	Median	All	0.858	0.962	.004	39	view →
PAAD	OS	Tertile	All	0.641	0.223	.002	35	view →
KIRC	DFS	Quartile	All	0.543	0.702	.002	35	view →
THCA	DFS	Tertile	II,III,IV	0.839	0.986	<.001	24	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	18	view →
HNSC	OS	Median	IV	0.371	0.611	.010	17	view →
KICH	OS	Quartile	All	0.322	0.946	.012	14	view →
LGG	DFS	Median	All	0.778	0.889	.004	14	view →
BRCA	DFS	Median	III,IV	0.916	0.839	.010	13	view →
LIHC	OS	Median	All	0.708	0.828	.012	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TERB1–DLBC (DFS)

Open the DLBC breakdown →