TEPSIN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TEPSIN protein abundance is significantly associated with the RNA expression of many other genes, with 2,604 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TEPSIN-associated genes across cancer lineages are NFKBIA, UPP1, and ZC3H12C. Each is linked with TEPSIN in more than 2 cancer types. Because this analysis shows association rather than direction, both TEPSIN-to-partner and partner-to-TEPSIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEPSIN versus NFKBIA in OV, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEPSIN→partner) and Y-score (partner→TEPSIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVNFKBIA →+1.703+1.178.001.00133
OVUPP1 →+0.940+0.794.007<.00133
OVZC3H12C →+1.425+0.676<.001.00632
BRCAEIF1AX-AS1 →+0.535+0.239<.001.00432
OVLINC01550 →+0.692+0.884.005.00632
UCECMEFV →+0.698+0.303.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,604 associations by consensus.

TEPSIN vs NFKBIA — OV

Per-sample scatter of TEPSIN vs NFKBIA in OV (Pearson r = 0.59).

Explore this scatter interactively →

Exploration