TEPP

Across TCGA pan-cancer cohorts, TEPP RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TEPP data layer compared with 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TEPP RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TEPP expression acts as an unfavorable survival marker, although some lineages such as LUAD and THYM show a favorable association.

LUAD, STAD, and THYM are the cancer types where TEPP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.846	0.737	<.001	39	view →
STAD	DFS	Tertile	All	0.362	0.558	.017	34	view →
THYM	DFS	Median	II,III,IV	0.964	0.819	.006	30	view →
COAD	OS	Quartile	IV	0.348	0.769	.001	29	view →
BLCA	OS	Quartile	III,IV	0.122	0.554	.002	27	view →
ESCA	OS	Tertile	IV	0.743	0.393	.024	24	view →
ACC	DFS	Tertile	II,III,IV	0.330	0.742	.015	20	view →
PCPG	DFS	Quartile	All	0.908	0.578	.014	17	view →
THCA	OS	Median	II,III,IV	0.990	0.774	.002	16	view →
KIRC	DFS	Median	II,III,IV	0.447	0.635	.017	16	view →
BRCA	OS	Quartile	III,IV	0.655	0.412	.014	14	view →
KICH	OS	Quartile	III,IV	1.000	0.450	.031	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TEPP–LUAD (DFS)

Open the LUAD breakdown →