TEP1

Across TCGA patient cohorts, TEP1 mutation is significantly associated with the RNA expression of many other genes, with 6,811 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEP1-associated genes across cancer lineages are PSMD14, EBP, and TYMS. Each is linked with TEP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TEP1-to-partner and partner-to-TEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD14 grouped by TEP1-low versus TEP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEP1→partner) and Y-score (partner→TEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	PSMD14 →	+0.413	+2.721	.005	.003	3	5
SKCM	EBP →	+0.440	+1.452	<.001	.003	3	5
STAD	TYMS →	+0.961	+3.940	<.001	<.001	3	5
STAD	SLC7A4 →	-1.025	-3.459	.002	.005	3	5
UCEC	AURKB →	+0.549	+1.306	<.001	<.001	3	5
UCEC	CDCA2 →	+0.927	+2.353	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,811 associations by consensus.

PSMD14 by TEP1 expression — BLCA

Explore this box plot interactively →