TEP1

Across TCGA pan-cancer cohorts, TEP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TEP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TEP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEP1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where TEP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+1.446	<.001	11	view →
COAD	Female	All	−0.964	<.001	8	view →
KIRC	All	All	+0.477	<.001	8	view →
CHOL	All	All	+1.785	<.001	5	view →
STAD	Male	III,IV	+1.426	.003	5	view →
LIHC	Female	All	+0.582	<.001	5	view →
KICH	All	All	−0.589	.003	2	view →
KIRP	All	All	+0.449	.004	2	view →
LUAD	All	All	+0.340	.003	2	view →
PRAD	All	All	+0.258	.042	2	view →
ESCA	All	All	+0.937	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TEP1–HNSC

Open the HNSC breakdown →