TENT5D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TENT5D mutation is significantly associated with the RNA expression of many other genes, with 5,347 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TENT5D-associated genes across cancer lineages are LINC01647, YARS1, and MRPL39. Each is linked with TENT5D in more than 3 cancer types. Because this analysis shows association rather than direction, both TENT5D-to-partner and partner-to-TENT5D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01647 grouped by TENT5D-low versus TENT5D-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5D→partner) and Y-score (partner→TENT5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCLINC01647 →+0.331+4.594<.001<.00134
UCECYARS1 →+0.620+2.223<.001<.00134
UCECMRPL39 →+0.474+2.673<.001<.00133
SKCMSKA1 →+0.787+2.725<.001.00233
ESCAOR5H2 →+0.268+3.584<.001.00233
ESCAMIR1208 →+0.796+3.106<.001.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,347 associations by consensus.

LINC01647 by TENT5D expression — LIHC

Box plot of LINC01647 in TENT5D-low vs TENT5D-high samples in LIHC.

Explore this box plot interactively →

Exploration