TENT5D

Across TCGA pan-cancer cohorts, TENT5D RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TENT5D data layer compared with 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TENT5D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TENT5D expression acts as an unfavorable survival marker, although some lineages such as PRAD and KIRP show a favorable association.

UCEC, LIHC, and DLBC are the cancer types where TENT5D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.351	0.811	<.001	66	view →
LIHC	OS	Tertile	II,III,IV	0.373	0.721	.002	60	view →
DLBC	OS	Tertile	III,IV	0.154	0.735	.010	34	view →
STAD	DFS	Quartile	All	0.270	0.601	.001	29	view →
PRAD	DFS	Tertile	All	0.923	0.754	<.001	18	view →
THCA	OS	Quartile	All	0.946	0.986	.008	15	view →
CHOL	DFS	Tertile	III,IV	0.163	0.779	.024	12	view →
KIRP	OS	Median	II,III,IV	0.814	0.272	.014	12	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →
UCS	DFS	Median	IV	0.891	0.491	.048	6	view →
LUSC	DFS	Median	II,III,IV	0.875	0.631	.029	6	view →
PCPG	DFS	Tertile	All	0.633	0.848	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TENT5D–UCEC (OS)

Open the UCEC breakdown →