TENT5C

Across TCGA pan-cancer cohorts, TENT5C Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TENT5C data layer compared with 29 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TENT5C Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TENT5C expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, SARC, and SKCM are the cancer types where TENT5C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.117	0.493	.002	13	view →
SARC	DFS	Median	All	0.190	0.612	.034	6	view →
SKCM	DFS	Median	All	0.943	0.717	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TENT5C–COAD (DFS)

Open the COAD breakdown →