TENT5C

Across TCGA cell cohorts, TENT5C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TENT5C-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, Protein targeting to ER, and SRP-dependent cotranslational protein targeting to membrane. Each is linked with TENT5C in more than 9 cancer types. Because this analysis shows association rather than direction, both TENT5C-to-partner and partner-to-TENT5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by TENT5C-low versus TENT5C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5C→partner) and Y-score (partner→TENT5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to endoplasmic reticulum stress →	+0.062	+0.945	.009	.005	3	10
OESOPHAGUS	Protein targeting to ER →	+0.102	+0.545	<.001	.004	2	10
SOFT_TISSUE	SRP-dependent cotranslational protein targeting to membrane →	+0.095	+0.349	<.001	.002	3	9
OESOPHAGUS	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.113	+0.613	.001	<.001	3	9
SKIN	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.074	+0.912	<.001	.003	2	10
URINARY_TRACT	COPII-coated vesicle budding →	+0.083	+0.550	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Response to endoplasmic reticulum stress by TENT5C expression — BONE

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