TENT5C

Across TCGA cell cohorts, TENT5C mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TENT5C-associated genes across cancer lineages are CFAP299, PRR23D1, and PTH. Each is linked with TENT5C in more than 1 cancer types. Because this analysis shows association rather than direction, both TENT5C-to-partner and partner-to-TENT5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFAP299 grouped by TENT5C-low versus TENT5C-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5C→partner) and Y-score (partner→TENT5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CFAP299 →	+0.061	+2.321	.009	.009	3	1
BLOOD_Myeloma	PRR23D1 →	+0.083	+2.762	.006	.005	3	1
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LUNG_SCLC	MRGPRX1 →	+0.216	+5.643	<.001	.002	3	1
LUNG_SCLC	MAGEB5 →	+0.020	+5.643	<.001	.002	3	1
SKIN	SPATA48 →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CFAP299 by TENT5C expression — BLOOD_Myeloma

Explore this box plot interactively →