TENT5B

Across TCGA pan-cancer cohorts, TENT5B Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TENT5B data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TENT5B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TENT5B expression acts as an unfavorable survival marker.

COAD, LUSC, and LIHC are the cancer types where TENT5B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.207	0.666	<.001	37	view →
LUSC	DFS	Median	III,IV	0.010	0.754	<.001	24	view →
LIHC	OS	Median	II,III,IV	0.033	0.716	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	III,IV	0.344	0.707	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TENT5B–COAD (DFS)

Open the COAD breakdown →