TENT4B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TENT4B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,548 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TENT4B-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening, Regulation of RNA export from nucleus, and Phosphatidylinositol biosynthetic process. Each is linked with TENT4B in more than 17 cancer types. Because this analysis shows association rather than direction, both TENT4B-to-partner and partner-to-TENT4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening grouped by TENT4B-low versus TENT4B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT4B→partner) and Y-score (partner→TENT4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYNegative regulation of nuclear-transcribed mRNA poly(A) tail shortening →+0.147+1.111<.001<.001318
BLOOD_LeukemiaRegulation of RNA export from nucleus →+0.115+0.590<.001<.001312
BREASTPhosphatidylinositol biosynthetic process →+0.050+0.653.001.002213
OESOPHAGUSEstablishment of protein localization to organelle →+0.064+0.654.002<.001312
BLOOD_LeukemiaRegulation of chromatin organization →+0.067+0.446.002.001311
KIDNEYGlycine betaine transport →+0.233+0.822<.001.002311
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,548 associations by consensus.

Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening by TENT4B expression — OVARY

Box plot of Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening in TENT4B-low vs TENT4B-high samples in OVARY.

Explore this box plot interactively →

Exploration