TENT4B

Across TCGA cell cohorts, TENT4B mutation is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TENT4B-associated genes across cancer lineages are MS4A13, FAM160A1, and OPN1MW2. Each is linked with TENT4B in more than 1 cancer types. Because this analysis shows association rather than direction, both TENT4B-to-partner and partner-to-TENT4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A13 grouped by TENT4B-low versus TENT4B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT4B→partner) and Y-score (partner→TENT4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MS4A13 →	+0.207	+5.228	<.001	.005	3	2
BLOOD_Leukemia	FAM160A1 →	+0.292	+3.947	<.001	.001	3	2
URINARY_TRACT	OPN1MW2 →	+0.020	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	1
LUNG_SCLC	SPACA1 →	+0.017	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

MS4A13 by TENT4B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →