TENM4

Across TCGA patient cohorts, TENM4 protein abundance is significantly associated with the RNA expression of many other genes, with 5,743 significant associations in total. OV shows the largest number of these associations.

The most reproducible TENM4-associated genes across cancer lineages are CTHRC1, COL1A1, and CSMD2. Each is linked with TENM4 in more than 4 cancer types. Because this analysis shows association rather than direction, both TENM4-to-partner and partner-to-TENM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TENM4 versus CTHRC1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM4→partner) and Y-score (partner→TENM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CTHRC1 →	+1.354	+0.387	.001	<.001	3	5
OV	COL1A1 →	+2.128	+0.440	.001	<.001	3	4
HNSC	CSMD2 →	+0.895	+0.628	<.001	<.001	3	4
OV	COL5A1 →	+1.562	+0.353	<.001	.001	3	4
OV	POSTN →	+1.642	+0.295	.005	<.001	3	4
BRCA	ITGA11 →	+1.295	+0.512	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,743 associations by consensus.

TENM4 vs CTHRC1 — OV

Explore this scatter interactively →