TENM2

Across TCGA patient cohorts, TENM2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,890 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TENM2-associated genes across cancer lineages are IL1R1, NECAB1, and MSRB3. Each is linked with TENM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TENM2-to-partner and partner-to-TENM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TENM2 versus IL1R1 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM2→partner) and Y-score (partner→TENM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL1R1 →	+0.798	+0.856	.004	<.001	3	3
PDAC	NECAB1 →	+0.751	+1.207	.002	.002	3	3
PDAC	MSRB3 →	+1.072	+1.161	<.001	<.001	3	3
BRCA	SNAI2 →	+1.278	+1.298	.002	<.001	3	3
HNSC	GPR68 →	+0.880	+0.522	<.001	<.001	3	3
HNSC	SH2D5 →	+0.727	+0.391	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,890 associations by consensus.

TENM2 vs IL1R1 — BRCA

Explore this scatter interactively →