TENM2

Across TCGA cell cohorts, TENM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,814 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TENM2-associated GO terms across cancer lineages are Secretion by tissue, Regulation of osteoclast development, and Establishment of protein localization to membrane. Each is linked with TENM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TENM2-to-partner and partner-to-TENM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Secretion by tissue grouped by TENM2-low versus TENM2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM2→partner) and Y-score (partner→TENM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Secretion by tissue →	-0.275	-2.569	.003	<.001	3	9
SKIN	Regulation of osteoclast development →	+0.128	+1.040	<.001	.001	3	8
CNS	Establishment of protein localization to membrane →	+0.040	+2.301	<.001	.001	3	8
CNS	Regulation of post-translational protein modification →	+0.045	+2.125	<.001	.002	2	9
LUNG_NSCLC_LUAD	Negative regulation of endodermal cell differentiation →	+0.834	+0.987	.004	.006	3	8
CNS	Endocytic recycling →	+0.066	+2.442	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,814 associations by consensus.

Secretion by tissue by TENM2 expression — LIVER

Explore this box plot interactively →