TEN1

Across TCGA cell cohorts, TEN1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEN1-associated genes across cancer lineages are DEFA1B. Each is linked with TEN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEN1-to-partner and partner-to-TEN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA1B grouped by TEN1-low versus TEN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEN1→partner) and Y-score (partner→TEN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DEFA1B →	+3.829	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DEFA1B by TEN1 expression — BLOOD_Leukemia

Explore this box plot interactively →