TELO2

Across TCGA cell cohorts, TELO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TELO2-associated GO terms across cancer lineages are Leading strand elongation, Pre-mRNA catabolic process, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with TELO2 in more than 15 cancer types. Because this analysis shows association rather than direction, both TELO2-to-partner and partner-to-TELO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leading strand elongation grouped by TELO2-low versus TELO2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TELO2→partner) and Y-score (partner→TELO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Leading strand elongation →	+0.200	+1.219	.001	.001	3	16
BONE	Pre-mRNA catabolic process →	+0.183	+1.076	<.001	<.001	3	15
OESOPHAGUS	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.143	+1.353	<.001	.001	3	14
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.130	+1.210	<.001	<.001	3	13
SOFT_TISSUE	RNA export from nucleus →	+0.111	+0.951	<.001	<.001	3	13
BONE	Positive regulation of DNA-directed DNA polymerase activity →	+0.170	+0.960	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Leading strand elongation by TELO2 expression — BONE

Explore this box plot interactively →