TELO2

Across TCGA cell cohorts, TELO2 mutation is significantly associated with the RNA expression of many other genes, with 160 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TELO2-associated genes across cancer lineages are CCDC185, C9orf92, and LCN1. Each is linked with TELO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TELO2-to-partner and partner-to-TELO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC185 grouped by TELO2-low versus TELO2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TELO2→partner) and Y-score (partner→TELO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC185 →	+0.048	+4.635	<.001	.003	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1
OESOPHAGUS	LCN1 →	+0.040	+4.906	<.001	.006	3	1
OESOPHAGUS	DEFB4A →	+0.653	+4.906	<.001	.006	3	1
OESOPHAGUS	ANKRD34C →	+0.016	+4.906	<.001	.006	3	1
LARGE_INTESTINE	DHRS7B →	+0.630	+3.451	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

CCDC185 by TELO2 expression — SOFT_TISSUE

Explore this box plot interactively →