TEKT3

Across TCGA cell cohorts, TEKT3 mutation is significantly associated with the RNA expression of many other genes, with 356 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEKT3-associated genes across cancer lineages are C20orf85, SSTR4, and OR13C7. Each is linked with TEKT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEKT3-to-partner and partner-to-TEKT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by TEKT3-low versus TEKT3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT3→partner) and Y-score (partner→TEKT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C20orf85 →	+0.056	+5.969	<.001	.001	3	1
BLOOD_Leukemia	SSTR4 →	+0.061	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR13C7 →	+0.023	+5.969	<.001	.001	3	1
BLOOD_Leukemia	ADAM7 →	+0.021	+4.922	.001	.009	3	1
LARGE_INTESTINE	MIOX →	+0.355	+3.212	<.001	.006	3	1
LARGE_INTESTINE	HMGXB4 →	+0.600	+3.237	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 356 associations by consensus.

C20orf85 by TEKT3 expression — BLOOD_Leukemia

Explore this box plot interactively →