TEK

Across TCGA patient cohorts, TEK protein abundance is significantly associated with the RNA expression of many other genes, with 7,153 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TEK-associated genes across cancer lineages are ADGRF5-AS1, SEMA3G, and VWF. Each is linked with TEK in more than 2 cancer types. Because this analysis shows association rather than direction, both TEK-to-partner and partner-to-TEK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEK versus ADGRF5-AS1 in CCRCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEK→partner) and Y-score (partner→TEK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADGRF5-AS1 →	+0.769	+0.533	<.001	<.001	3	3
CCRCC	SEMA3G →	+1.724	+0.759	<.001	<.001	3	3
CCRCC	VWF →	+1.248	+0.615	<.001	<.001	3	3
CCRCC	MYCT1 →	+0.783	+0.371	<.001	<.001	3	3
LSCC	SOCS2 →	+0.964	+0.491	<.001	<.001	3	3
LSCC	CD93 →	+0.732	+0.425	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,153 associations by consensus.

TEK vs ADGRF5-AS1 — CCRCC

Explore this scatter interactively →