TEFM

Across TCGA patient cohorts, TEFM protein abundance is significantly associated with the RNA expression of many other genes, with 14,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TEFM-associated genes across cancer lineages are SSPN, MNDA, and LITAF. Each is linked with TEFM in more than 5 cancer types. Because this analysis shows association rather than direction, both TEFM-to-partner and partner-to-TEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEFM versus SSPN in BRCA, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEFM→partner) and Y-score (partner→TEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SSPN →	-0.691	-0.292	.003	.003	3	6
OV	MNDA →	-1.048	-0.545	.004	.001	3	5
OV	LITAF →	-0.741	-0.775	<.001	<.001	3	5
HNSC	IFFO1 →	-0.549	-0.337	<.001	.001	3	5
BRCA	MAN1C1 →	-0.657	-0.231	.004	.007	3	5
LUAD	ABCA8 →	-0.943	-0.415	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,177 associations by consensus.

TEFM vs SSPN — BRCA

Explore this scatter interactively →