TEF

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TEF protein abundance is significantly associated with the RNA expression of many other genes, with 2,254 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TEF-associated genes across cancer lineages are LGALSL, ITPKA, and TLL1. Each is linked with TEF in more than 1 cancer types. Because this analysis shows association rather than direction, both TEF-to-partner and partner-to-TEF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEF versus LGALSL in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEF→partner) and Y-score (partner→TEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADLGALSL →+0.741+0.444<.001<.00132
LUADITPKA →-2.019-0.458.003.00332
CCRCCTLL1 →+1.036+0.292<.001<.00132
BRCAHNRNPAB →-0.500-0.394.002<.00132
BRCAIFI30 →-0.792-0.410.002.00232
LSCCARHGEF37 →+0.868+0.356<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,254 associations by consensus.

TEF vs LGALSL — LUAD

Per-sample scatter of TEF vs LGALSL in LUAD (Pearson r = 0.52).

Explore this scatter interactively →

Exploration