TEDC2

Across TCGA cell cohorts, TEDC2 mutation is significantly associated with the RNA expression of many other genes, with 1,119 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEDC2-associated genes across cancer lineages are CRYBB1, HTR1A, and HSFY1. Each is linked with TEDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEDC2-to-partner and partner-to-TEDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by TEDC2-low versus TEDC2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEDC2→partner) and Y-score (partner→TEDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CRYBB1 →	+0.026	+4.906	<.001	.006	3	1
BLOOD_Lymphoma	HTR1A →	+0.013	+4.058	.002	.009	3	1
SKIN	HSFY1 →	+0.013	+6.022	<.001	.001	3	1
SKIN	CYLC1 →	+0.013	+5.415	<.001	.004	3	1
SKIN	FAM205C →	+0.045	+4.977	<.001	.007	3	1
SKIN	MEIKIN →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,119 associations by consensus.

CRYBB1 by TEDC2 expression — OESOPHAGUS

Explore this box plot interactively →