TECR

Across TCGA patient cohorts, TECR mutation is significantly associated with the RNA expression of many other genes, with 925 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TECR-associated genes across cancer lineages are RNU6-974P, RNU6-626P, and MIR4477A. Each is linked with TECR in more than 1 cancer types. Because this analysis shows association rather than direction, both TECR-to-partner and partner-to-TECR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-974P grouped by TECR-low versus TECR-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECR→partner) and Y-score (partner→TECR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-974P →	+0.343	+8.471	<.001	.005	3	2
SKCM	RNU6-626P →	+0.368	+5.624	<.001	.002	3	2
BLCA	MIR4477A →	+0.507	+3.872	.007	.008	3	2
UCEC	RNA5SP405 →	+0.288	+3.167	<.001	.005	3	2
UCEC	RNU6-933P →	+0.371	+2.032	.002	.002	3	2
UCEC	RNU6-1122P →	+0.209	+2.452	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 925 associations by consensus.

RNU6-974P by TECR expression — BRCA

Explore this box plot interactively →