TECR

Across TCGA cell cohorts, TECR RNA expression is significantly associated with the go_rna of many other GO terms, with 2,566 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TECR-associated GO terms across cancer lineages are Negative regulation of transcription initiation-coupled chromatin remodeling, Dolichyl monophosphate biosynthetic process, and Pentose-phosphate shunt, oxidative branch. Each is linked with TECR in more than 7 cancer types. Because this analysis shows association rather than direction, both TECR-to-partner and partner-to-TECR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription initiation-coupled chromatin remodeling grouped by TECR-low versus TECR-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TECR→partner) and Y-score (partner→TECR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.182	+0.875	<.001	<.001	3	8
CNS	Dolichyl monophosphate biosynthetic process →	+0.094	+0.424	.002	.005	3	8
SKIN	Pentose-phosphate shunt, oxidative branch →	+0.094	+0.582	<.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of protein localization to chromatin →	+0.076	+0.493	.004	.006	3	7
BLOOD_Lymphoma	Attachment of GPI anchor to protein →	+0.119	+0.560	<.001	<.001	3	7
PANCREAS	Positive regulation of protein folding →	+0.087	+0.709	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,566 associations by consensus.

Negative regulation of transcription initiation-coupled chromatin remodeling by TECR expression — BREAST

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