TDRP

Across TCGA cell cohorts, TDRP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TDRP-associated genes across cancer lineages are GSG1L2 and ASB17. Each is linked with TDRP in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRP-to-partner and partner-to-TDRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by TDRP-low versus TDRP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRP→partner) and Y-score (partner→TDRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GSG1L2 by TDRP expression — LARGE_INTESTINE

Explore this box plot interactively →