TDRD12

Across TCGA patient cohorts, TDRD12 mutation is significantly associated with the RNA expression of many other genes, with 4,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TDRD12-associated genes across cancer lineages are RN7SL580P, SMIM28, and RNA5SP411. Each is linked with TDRD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRD12-to-partner and partner-to-TDRD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL580P grouped by TDRD12-low versus TDRD12-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD12→partner) and Y-score (partner→TDRD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL580P →	+0.160	+5.760	<.001	.003	3	2
CESC	SMIM28 →	+0.147	+4.069	<.001	.005	3	2
UCEC	RNA5SP411 →	+0.802	+1.531	<.001	.005	3	2
SARC	TXNL4AP1 →	+0.379	+5.345	<.001	.005	3	2
CESC	MIR580 →	+0.721	+4.101	<.001	.004	3	1
CESC	RNA5SP198 →	+0.224	+4.559	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,170 associations by consensus.

RN7SL580P by TDRD12 expression — BRCA

Explore this box plot interactively →