TCTN1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TCTN1 mutation is significantly associated with the RNA expression of many other genes, with 1,869 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCTN1-associated genes across cancer lineages are SPATA16, RPS14P5, and RNU6-451P. Each is linked with TCTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTN1-to-partner and partner-to-TCTN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTN1→partner) and Y-score (partner→TCTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCSPATA16 →+0.134+5.231<.001<.00132
LUSCRPS14P5 →+0.146+4.259.002.00132
HNSCRNU6-451P →+0.308+4.182<.001.00232
BRCAPRELID3BP6 →+0.136+3.963.003.00732
CESCRN7SL111P →+0.226+4.376<.001.00232
CESCWRBP1 →+0.239+4.649<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,869 associations by consensus.

Exploration