TCTEX1D1

Across TCGA patient cohorts, TCTEX1D1 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCTEX1D1-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, ATM, and 14-3-3_beta. Each is linked with TCTEX1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTEX1D1-to-partner and partner-to-TCTEX1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by TCTEX1D1-low versus TCTEX1D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTEX1D1→partner) and Y-score (partner→TCTEX1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.398	+1.710	.033	.025	3	2
UCEC	ATM →	-0.350	-3.156	.036	.018	3	2
UCEC	14-3-3_beta →	-0.090	-1.973	.014	.029	3	1
UCEC	EGFR_pY1068 →	-0.270	-1.847	.003	.008	3	1
UCEC	eIF4G →	+0.301	+1.502	.008	.030	3	1
UCEC	FoxM1 →	+0.291	+3.594	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Acetyl-a-Tubulin-Lys40 by TCTEX1D1 expression — UCEC

Explore this box plot interactively →