TCTEX1D1

Across TCGA pan-cancer cohorts, TCTEX1D1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TCTEX1D1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TCTEX1D1 RNA is repressed in tumor relative to normal tissue. In most cancer types TCTEX1D1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and LIHC are the cancer types where TCTEX1D1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TCTEX1D1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−1.331	<.001	11	view →
LUSC	Female	II,III,IV	−1.709	<.001	9	view →
LIHC	Male	II,III,IV	−1.512	<.001	9	view →
UCEC	All	All	−1.517	<.001	6	view →
BLCA	Male	All	−0.465	.001	6	view →
BRCA	All	All	−0.261	<.001	6	view →
KICH	All	All	−0.355	<.001	5	view →
KIRC	All	All	+0.225	<.001	4	view →
CHOL	All	All	−1.252	<.001	3	view →
STAD	Male	II,III,IV	+0.158	.035	1	view →
THCA	All	All	+0.066	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TCTEX1D1–LUAD

Open the LUAD breakdown →