TCP11L2

Across TCGA patient cohorts, TCP11L2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,314 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TCP11L2-associated genes across cancer lineages are MICU1, SLC31A1, and HVCN1. Each is linked with TCP11L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCP11L2-to-partner and partner-to-TCP11L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCP11L2 versus MICU1 in PDAC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP11L2→partner) and Y-score (partner→TCP11L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MICU1 →	+0.588	+0.405	<.001	<.001	3	3
OV	SLC31A1 →	-0.768	-0.551	<.001	.001	3	3
UCEC	HVCN1 →	+0.519	+0.459	.006	.001	3	2
HNSC	PLD2 →	+0.743	+0.321	<.001	<.001	3	2
HNSC	TPPP2 →	+0.288	+0.277	.008	<.001	3	2
GBM	AKAP5 →	-0.689	-0.313	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,314 associations by consensus.

TCP11L2 vs MICU1 — PDAC

Explore this scatter interactively →