TCP11L1

Across TCGA patient cohorts, TCP11L1 mutation is significantly associated with the RNA expression of many other genes, with 3,962 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCP11L1-associated genes across cancer lineages are RNU6-1318P, RNU6-382P, and RNU6-1067P. Each is linked with TCP11L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCP11L1-to-partner and partner-to-TCP11L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1318P grouped by TCP11L1-low versus TCP11L1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP11L1→partner) and Y-score (partner→TCP11L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1318P →	+0.248	+4.588	.003	.008	3	3
BRCA	RNU6-382P →	+0.358	+8.471	<.001	.005	3	2
STAD	RNU6-1067P →	+0.368	+3.705	.007	.003	3	2
BLCA	BNIP3P6 →	+0.100	+5.618	<.001	.002	3	2
BLCA	OR7E8P →	+0.090	+5.435	<.001	<.001	3	2
UCEC	MIR4445 →	+0.133	+4.019	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,962 associations by consensus.

RNU6-1318P by TCP11L1 expression — BLCA

Explore this box plot interactively →