TCP11

Across TCGA patient cohorts, TCP11 protein abundance is significantly associated with the RNA expression of many other genes, with 10,490 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TCP11-associated genes across cancer lineages are KLHDC1, INMT, and CRY2. Each is linked with TCP11 in more than 5 cancer types. Because this analysis shows association rather than direction, both TCP11-to-partner and partner-to-TCP11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCP11 versus KLHDC1 in CCRCC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP11→partner) and Y-score (partner→TCP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KLHDC1 →	-0.861	-0.887	<.001	<.001	3	6
LSCC	INMT →	-1.422	-0.645	<.001	<.001	3	6
UCEC	CRY2 →	-0.912	-0.473	<.001	.003	3	5
UCEC	ORC6 →	+1.027	+0.774	.004	.004	3	5
CCRCC	RASL12 →	-1.108	-0.765	<.001	<.001	3	5
LSCC	EZH2 →	+0.992	+0.478	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,490 associations by consensus.

TCP11 vs KLHDC1 — CCRCC

Explore this scatter interactively →