TCP10L2

Across TCGA patient cohorts, TCP10L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,915 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TCP10L2-associated GO terms across cancer lineages are Autophagy of mitochondrion, Negative regulation of protein ubiquitination, and Protein-containing complex disassembly. Each is linked with TCP10L2 in more than 16 cancer types. Because this analysis shows association rather than direction, both TCP10L2-to-partner and partner-to-TCP10L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by TCP10L2-low versus TCP10L2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP10L2→partner) and Y-score (partner→TCP10L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Autophagy of mitochondrion →	+0.067	+0.188	<.001	<.001	3	16
STAD	Negative regulation of protein ubiquitination →	+0.042	+0.136	<.001	<.001	3	16
STAD	Protein-containing complex disassembly →	+0.044	+0.134	<.001	<.001	3	16
STAD	Organelle disassembly →	+0.071	+0.207	<.001	<.001	2	17
STAD	Import into nucleus →	+0.045	+0.134	<.001	<.001	3	16
STAD	Obsolete histone H3-K4 methylation →	+0.067	+0.262	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,915 associations by consensus.

Autophagy of mitochondrion by TCP10L2 expression — STAD

Explore this box plot interactively →