TCP10L2

Across TCGA cell cohorts, TCP10L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 184 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible TCP10L2-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Protein localization to ciliary transition zone, and Serotonin biosynthetic process. Each is linked with TCP10L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCP10L2-to-partner and partner-to-TCP10L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by TCP10L2-low versus TCP10L2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP10L2→partner) and Y-score (partner→TCP10L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Chromosomal 5-methylcytosine DNA demethylation pathway →	-0.123	-0.067	.002	.007	3	2
LARGE_INTESTINE	Protein localization to ciliary transition zone →	-0.035	-0.067	.007	.007	3	2
LARGE_INTESTINE	Serotonin biosynthetic process →	+0.915	+0.072	.002	.004	3	2
LARGE_INTESTINE	Indole-containing compound biosynthetic process →	+1.068	+0.072	<.001	.004	3	2
LARGE_INTESTINE	Negative regulation of monoatomic ion transport →	+0.041	+0.068	<.001	.006	3	2
LIVER	Protein localization to cilium →	-0.057	-0.521	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by TCP10L2 expression — LARGE_INTESTINE

Explore this box plot interactively →