TCP10L2

Across TCGA cell cohorts, TCP10L2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCP10L2-associated genes across cancer lineages are OR11H1 and OR11H2. Each is linked with TCP10L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCP10L2-to-partner and partner-to-TCP10L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by TCP10L2-low versus TCP10L2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP10L2→partner) and Y-score (partner→TCP10L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.083	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR11H2 →	+0.101	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR11H1 by TCP10L2 expression — BLOOD_Leukemia

Explore this box plot interactively →