TCP1

Across TCGA pan-cancer cohorts, TCP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TCP1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TCP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TCP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

LUAD, COAD, and HNSC are the cancer types where TCP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.449	0.788	.003	27	view →
COAD	DFS	Median	III,IV	1.000	0.843	.042	12	view →
HNSC	OS	Median	All	1.000	0.449	.023	12	view →
GBM	OS	Tertile	All	0.463	0.633	.027	5	view →
CCRCC	DFS	Median	All	0.661	0.809	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TCP1–LUAD (OS)

Open the LUAD breakdown →