Across TCGA patient cohorts, TCN2 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,785 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TCN2-associated proteins across cancer lineages are CTSZ, DMXL2, and PLEKHG2_T445. Each is linked with TCN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TCN2-to-partner and partner-to-TCN2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN2→partner) and Y-score (partner→TCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSZ →	+0.580	+0.460	<.001	<.001	3	4
OV	DMXL2 →	+0.364	+0.542	.006	.002	3	3
LUAD	PLEKHG2_T445 →	+0.749	+0.441	<.001	<.001	3	3
GBM	SMC4 →	-0.638	-0.468	.008	<.001	3	3
GBM	UBR7 →	-0.480	-0.429	.001	.001	3	3
GBM	RBMX_S88 →	-0.438	-0.525	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,785 associations by consensus.

Exploration

TCN2 survival (RNA) · tumor vs normal (RNA) · all TCN2 data types