TCF25

Across TCGA patient cohorts, TCF25 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,137 significant associations in total. OV shows the largest number of these associations.

The most reproducible TCF25-associated GO terms across cancer lineages are Nucleotide-sugar biosynthetic process, Oxidative RNA demethylation, and DNA alkylation repair. Each is linked with TCF25 in more than 22 cancer types. Because this analysis shows association rather than direction, both TCF25-to-partner and partner-to-TCF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-sugar biosynthetic process grouped by TCF25-low versus TCF25-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF25→partner) and Y-score (partner→TCF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Nucleotide-sugar biosynthetic process →	+0.054	+1.066	<.001	<.001	2	23
UCS	Oxidative RNA demethylation →	+0.052	+0.497	.006	.006	1	23
ACC	DNA alkylation repair →	+0.075	+1.127	<.001	<.001	3	21
TGCT	Malonyl-CoA metabolic process →	+0.040	+0.578	<.001	<.001	3	20
ACC	Peptidyl-methionine modification →	+0.057	+1.041	<.001	<.001	3	20
ESCA	N-terminal protein amino acid modification →	+0.031	+0.347	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,137 associations by consensus.

Nucleotide-sugar biosynthetic process by TCF25 expression — ACC

Explore this box plot interactively →