TCF25

Across TCGA cell cohorts, TCF25 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,182 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TCF25-associated GO terms across cancer lineages are Vesicle uncoating, Negative regulation of calcium ion export across plasma membrane, and Viral transcription. Each is linked with TCF25 in more than 14 cancer types. Because this analysis shows association rather than direction, both TCF25-to-partner and partner-to-TCF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle uncoating grouped by TCF25-low versus TCF25-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF25→partner) and Y-score (partner→TCF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Vesicle uncoating →	+0.142	+0.879	<.001	<.001	3	15
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.066	+0.946	<.001	<.001	3	13
BONE	Viral transcription →	+0.132	+0.882	.001	.001	3	13
BONE	Late viral transcription →	+0.115	+0.793	<.001	<.001	3	13
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.132	+0.981	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.153	+0.680	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,182 associations by consensus.

Vesicle uncoating by TCF25 expression — SOFT_TISSUE

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