TCF21

Across TCGA cell cohorts, TCF21 RNA expression is significantly associated with the go_rna of many other GO terms, with 312 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TCF21-associated GO terms across cancer lineages are Regulation of dendritic cell chemotaxis, Determination of dorsal identity, and Metanephric glomerulus morphogenesis. Each is linked with TCF21 in more than 3 cancer types. Because this analysis shows association rather than direction, both TCF21-to-partner and partner-to-TCF21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendritic cell chemotaxis grouped by TCF21-low versus TCF21-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF21→partner) and Y-score (partner→TCF21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of dendritic cell chemotaxis →	+0.130	+0.281	.003	.006	3	3
STOMACH	Determination of dorsal identity →	+0.911	+0.422	.004	.003	3	3
SOFT_TISSUE	Metanephric glomerulus morphogenesis →	+0.836	+1.460	<.001	<.001	3	3
SOFT_TISSUE	Metanephric glomerulus vasculature morphogenesis →	+0.836	+1.460	<.001	<.001	3	3
SOFT_TISSUE	Metanephric glomerular capillary formation →	+0.836	+1.460	<.001	<.001	3	3
BREAST	Positive regulation of cell chemotaxis to fibroblast growth factor →	+0.925	+0.008	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 312 associations by consensus.

Regulation of dendritic cell chemotaxis by TCF21 expression — STOMACH

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